The Longevity Reality Radar
46 approaches, rated by evidence.

NAD+ boosters (NMN, NMNH, NRH)

Next-gen NAD+ boosters (NMN / NMNH / NRH). Aging itself. Reviewed Jul 2026.

Trials show these supplements raise NAD+ levels 2 to 3 times, but there is no human outcome data on lifespan or disease.

Stage
Supplement, early trials
Rung: Experimental. Animal, lab or theoretical. Years away, if ever.
Evidence grade
C
NAD levels only
Small or uncontrolled human data, or strong animal data. How grades work.

What it is

Precursors that raise cellular NAD+, a coenzyme central to energy metabolism and DNA repair that falls with age.

The evidence

Clinical trials show NAD+ levels can be raised 2–3x; hard outcomes (lifespan, disease) in humans remain unproven. Strong consumer adoption ahead of definitive efficacy data.

What you can do today

Not available for this use, and years away if it arrives at all. Anything sold today with this claim is not backed by human evidence for it.

Sources

No primary paper or registry record is linked for this entry yet. The evidence summary names the studies it relies on.

Change history

No ladder moves or corrections logged for this entry yet. Changes are dated on the change log.

Related

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